Human Endocannabinoid System

The Endocannabinoid System, aka ECS:
🌱 Humans, like all mammals, produce endogenous (internal) cannabinoids (called endocannabinoids)
🌱 These are similar to cannabinoids found in herbal cannabis
🌱 Endocannabinoids are also involved in temperature control, pain modulation, appetite, nausea, cellular migration, control of inflammation, and more
🌱 The ECS has two primary receptors known as CB1
and CB2
As cannabinoids interact with this body system, they promote homeostasis in the body (homeostasis refers to stability, balance or equilibrium within cells or the body).
🌱 CB1 receptors bind primarily to the brains and nervous system, but are also found in the spleen, our white blood cells, the gastrointestinal and urinary tracts, lungs, kidneys, liver, our endocrine glands and parts of our reproductive system.
🌱 Pediatric Blood Cancer 2018: CB1 expression has been observed in the areas of the CNS that are engaged in the modulation of motor skills, memory, sleep, learning, emotions, perception, and endocrine functions
🌱 Cancer Medicine 2018: Studies using mice suggest the CB1 receptor plays a role in depression, anxiety, feeding and cognition
🌱 CB2 receptors interact primarily with the immune system and are found in the tonsils, the spleen, and on white blood cells.
🌱 CB2 receptors also play a role in inflammation.
🌱 Expression of CB2 receptors is most prominent in the immune system where they act as immunomodulators great news for autoimmune