The first clinically studied PMS/period supplement—all natural AND science-backed. Only take it when you need it, not all month long. Semaine PMS & Period Support capsules help lessen cramping, bloating, fatigue, mood swings, and headaches the week of your period. Made by people with painful periods for people with painful periods.. Includes Boswellia which soothes the intestines and supports your digestion; Silymarin supports your liver, which filters estrogen; Quercetin lessens the natural histamine response and Resveratrol, an antioxidant found in red wine and chocolate, helps your body heal. And the best part? It's natural and it works.